Comparison of between using exome and microarray derived variant data.

The images below show the maternal and paternal origin of the chromosome in four siblings using data derived from Exome variants data (on the left) or Affymetrix SNP 6.0 microarray genotype data (on the right) as analysed by Phaser. While the overall pattern is roughly comparable, there are notable differences between the data sets. This is the result of the lower number of variants, unevent coverage and increase miscalled rate of the data derived from the exome data when compared to the better microarray data. It is likely that the situation will be improved if whole genome sequence data is used instead of exome data.

Chromosome 1
Chromosome 2
Chromosome 3
Chromosome 4
Chromosome 5
Chromosome 6
Chromosome 7
Chromosome 8
Chromosome 9
Chromosome 10
Chromosome 11
Chromosome 12
Chromosome 13
Chromosome 14
Chromosome 15
Chromosome 16
Chromosome 17
Chromosome 18
Chromosome 19
Chromosome 20
Chromosome 21
Chromosome 22